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Alfatradiol is a synthetic derivative of the female hormone estradiol, which was specially developed for the treatment of hair loss, in particular androgenetic alopecia. This product is applied topically, i.e. directly to the scalp, and does not enter the bloodstream, so there are no systemic hormonal effects.
The mode of action of alfatradiol is based on the inhibition of the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT). DHT plays a central role in the shrinkage of hair follicles, which ultimately leads to hair loss. By reducing DHT production, alfatradiol can slow down or stop hair loss.
Alfatradiol is usually offered as a solution for topical application. It is recommended to apply the product once a day to the affected areas of the scalp. Continuous application is crucial, as hair loss can resume if treatment is discontinued.
The advantages of alfatradiol lie in its non-hormonal effect and ease of use. As it does not have a systemic effect, hormonal side effects are not to be expected. The application as a solution is uncomplicated and can be easily integrated into everyday life. Side effects are generally mild and include skin irritation or itching at the application site. Serious side effects are rare.
In summary, alfatradiol is an effective option for the treatment of androgenetic hair loss, especially for people who prefer treatment without systemic hormonal effects. Regular and continuous use is important in order to achieve lasting results.